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Buy Bulk CJC-1295 NO-DAC 2mg

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Buy Bulk CJC-1295 NO-DAC (No Promo Codes):

Unit Size 2 mg/vial
Unit Quantity 1 vial
Purity (Mass Spectrometry and UV) 99.18%
Sequence H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-
Gln-Leu- Ser-Ala-Arg-Lys-Leu--Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Molecular Formula C152H252N44O42
Appearance Lyophilized White Powder
Source Chemical Synthesis
Storage Lyophilized CJC-1295 NO-DAC is Stable at room
Temperature for 90 days, however it is best to store in a freezer
below - 8c for any extended
period of time.
Terms The products we offer are intended for laboratory
research use only. Please familiarize yourself with
our terms of service prior to ordering.

CJC-1295 NO-DAC 2mg (Bulk)

All content and product information provided on this website are for informational and educational research purposes only. Products are not intended for human or animal consumption, diagnostic use, or therapeutic use.
View Research Overview & References

CJC-1295 NO-DAC is a synthetic peptide that contains the first 29 amino acids of the endogenous growth hormone-releasing hormone (GHRH).1 Known as modified growth-releasing factor 1-29 (MOD GRF 1-29), this version does not include the drug affinity complex (DAC), resulting in a shorter half-life. Its molecular weight is 3365.87 g/mol. Without DAC, CJC-1295 NO-DAC is studied in laboratory settings to model a more physiological response profile in in vitro and in vivo (animal) research.2

Animal Model Research

CJC-1295 NO-DAC is studied for its stimulation of growth hormone release due to its GHRH-like sequence. Animal research has examined single-dose administration in relation to growth hormone level changes, noting that the pattern did not disturb the animal's natural circadian hormone release rhythm.3 In a study using a GHRH-deficient mouse model, daily CJC-1295 administration was associated with body length and weight metrics comparable to wild-type control animals.1 Additional research has examined CJC-1295's association with insulin-like growth factor-1 (IGF-1) secretion in animal models, relevant to metabolic and growth-related research.4

Important Notice

This product is intended strictly for in vitro and in vivo (animal) laboratory research and is not suitable for human or veterinary applications. These findings do not establish safety, efficacy, or suitability for any human or animal application, and this product has not been evaluated by the FDA or any regulatory agency.

Product Information

CJC-1295 NO-DAC is supplied as a lyophilized powder at a concentration of 2 mg per vial, available in bulk quantity.

References

1. Alba M, Fintini D, Sagazio A, et al. Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1290-1294.
2. Jette L, Leger R, Thibaudeau K, et al. Human growth hormone-releasing factor (hGRH) 1-29 - Albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: Identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. 2005 Jul;146(7):3052-3058.
3. Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab. 2006;91(12):4792-4797.
4. Campbell RM, Stricker P, Miller R, et al. Enhanced stability and potency of novel growth hormone-releasing factor (GRF) analogues derived from rodent and human GRF sequences. Peptides. 1994;15(3):489-495.