Blend CJC 1295 NO DAC 5MG with GHRP-2 5MG

CJC-1295 NO/DAC with GHRP-2 is a synthetic analog of growth hormone-releasing hormone (GHRH) combined with growth hormone-releasing peptide-2 (GHRP-2). CJC-1295 is composed of 30 amino acids and has a molecular weight of 3647.16 g/mol. This peptide is derived from sermorelin (GHRH 1-29) and is formulated without a drug affinity complex (DAC), resulting in a shorter half-life compared to CJC-1295 with DAC, which binds to albumin to prolong its activity.⁽¹⁾ This formulation allows researchers to study short-term effects and pathways related to growth hormone release.⁽²⁾

Research indicates that CJC-1295 effectively promotes growth hormone (GH) release while maintaining normal levels of insulin-like growth factor-1 (IGF-1) secretion.⁽³⁾ GHRP-2, a synthetic ghrelin agonist, binds to the growth hormone secretagogue receptor, stimulating both GH release and appetite.⁽⁴⁾ When used together, these peptides enhance the secretion of both growth hormone and IGF-1, making them valuable tools for studying metabolic pathways and muscle function.

Both in vitro and in vivo studies have explored the potential of CJC-1295 and GHRP-2 for muscle strengthening, fat reduction, immune system modulation, and improved cardiac function. Research suggests these peptides may enhance lean muscle mass while reducing fat. However, it's important to emphasize that these studies were conducted under controlled research conditions and do not imply approval for clinical or therapeutic use.^(2,5)

CJC-1295 NO/DAC with GHRP-2 is intended strictly for in vitro laboratory research only and is not for human consumption or therapeutic use. Researchers utilize this product to investigate the biochemical effects of growth hormone pathways under experimental conditions.

CJC-1295 NO/DAC with GHRP-2 is supplied as a white lyophilized powder at a concentration of 10 mg per vial (5 mg x 2) for use in in vitro studies.

References:

1. Jette L, Leger R, Thibaudeau K, et al. *Human Growth Hormone-Releasing Factor (hGRH) 1-29 - Albumin Bioconjugates Activate the GRF Receptor on the Anterior Pituitary in Rats: Identification of CJC-1295 as a Long-Lasting GRF Analog.* Endocrinology. 2005 Jul;146(7):3052-3058.
2. Teichman SL, Neale A, Lawrence B, et al. *Prolonged Stimulation of Growth Hormone (GH) and Insulin-Like Growth Factor I Secretion by CJC-1295, a Long-Acting Analog of GH-Releasing Hormone, in Healthy Adults.* J Clin Endocrinol Metab. 2006 Mar;91(3):799-805.
3. Alba M, Fintini D, Sagazio A, et al. *Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse.* Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1290-4.
4. Laferrere B, Abraham C, Russell CD, Bowers CY. *Growth Hormone Releasing Peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.* J Clin Endocrinol Metab. 2005 Feb;90(2):611-614.
5. Sigalos JT, Pastuszak AW, Allison A, et al. *Growth Hormone Secretagogue Treatment in Hypogonadal Men Raises Serum Insulin-Like Growth Factor-1 Levels.* Am J Mens Health. 2017 Nov;11(6):1752-1757.