Thymosin Beta 4 (TB500) 5mg
Buy Thymosin Beta 4 (TB500) 5MG :
| Unit Size | 5 mg/ vial |
| Unit Quantity | 1 vial |
| Purity (Mass Spectrometry and UV) | 99.87% |
| Sequence | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser- Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys- Glu-Thr-Ile-Glu-Gln-Glu-Lys- Gln-Ala-Gly-Glu-Ser-OH |
| Molecular Formula | C212H350N56O78S |
| Appearance | Lyophilized White Powder |
| Source | Chemical Synthesis |
| Storage | Lyophilized TB500 is stable at room Temperature for 90 days, however it is best to store in a freezer below - 8c for any extended period of time. |
| Terms | The products we offer are intended for laboratory research use only. Please familiarize yourself with our terms of service prior to ordering. |
Thymosin Beta 4 (TB500) 5mg
View Research Overview & References
Thymosin Beta 4 is a protein isolate from the mammalian thymus gland, encoded by the TMSB4X gene and part of the thymosin family of low molecular weight acidic compounds. Found in all cell types except red blood cells, this protein is studied exclusively in laboratory research settings.1
Cell Motility and Differentiation Research
Thymosin Beta 4 is studied for its role in cell motility and differentiation, forming a 1:1 complex with monomeric actin (G-actin) to act as an actin buffer. This complex inhibits the polymerization of actin into filaments (F-actin), maintaining a pool of actin monomers relevant to laboratory research on cell migration and cell differentiation pathways. This mechanism is of interest to researchers examining cell differentiation, including in pluripotent cells, neural cells, and osteocyte models.2,3 TB500, a laboratory-grade synthetic version, contains 43 amino acids and has a molecular weight slightly above 4.9 kDa.
Actin Regulation Research
Research has examined thymosin beta 4's role in actin regulation in cell models relevant to inflammatory signaling research.3
Important Notice
TB500 is intended exclusively for in vitro laboratory research use only. It is not approved for human or animal use, diagnostic use, or therapeutic use, and has not been evaluated for safety or efficacy in humans or animals.
Product Information
TB500 is available as a white lyophilized powder with a concentration of 5 mg per vial, strictly for in vitro laboratory use.
References
1. Goldstein AL, Slater FD, White A. Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin). Proc Natl Acad Sci U S A. 1966;56(3):1010-7.
2. Huff T, Müller CS, Otto AM, Netzker R, Hannappel E. Beta-Thymosins, small acidic peptides with multiple functions. Int J Biochem Cell Biol. 2001 Mar;33(3):205-20.
3. Belsky JB, Rivers EP, Filbin MR, Lee PJ, Morris DC. Thymosin beta 4 regulation of actin in sepsis. Expert Opin Biol Ther. 2018 Jul;18(sup1):193-197.
Storage Case (10)$9.99
