Buy Bulk MGF (Mechano Growth Factor) 2mg

Mechano Growth Factor (MGF) is a synthetic peptide that mimics the C-terminal portion of the MGF protein, an isoform of insulin-like growth factor 1 (IGF-1). This peptide consists of 24 amino acids and is studied in vitro and in vivo (animal) laboratory research, with applications focused on examining cellular mechanisms related to muscle cell biology.

Muscle Cell Research

In vitro studies have examined MGF's association with cell proliferation, migration, and resistance to injury-induced cell death markers. Laboratory research has studied MGF's effects on satellite cell numbers in cultured muscle cell models, contributing to basic research on muscle tissue repair mechanisms.¹

Cell Transplantation Research

Animal model research using synthetic MGF E-peptide has examined its effects on myogenic precursor cell transplantation outcomes in mice, including markers of cell proliferation, migration, and differentiation timing following transplantation.²

Tendon Cell Research

Laboratory research has examined MGF's effects on tendon-like cell structures in animal models. Researchers assessed tendon morphology, collagen arrangement, and cell growth markers, observing changes in these markers in MGF-treated groups.^3,4

Neuronal Cell Stress Research

MGF has also been examined in vitro for its effects on neuronal cell models under neurotoxic stress conditions. Laboratory research has examined MGF's association with HO-1 expression, a marker of cellular stress-response pathways, and its relationship to mitochondrial function markers and cell death markers in these models.⁵

Cell Signaling Pathway Research

Additional in vitro research has examined MGF's association with Akt signaling pathway activation, a pathway studied in relation to cell survival and growth signaling, contributing to basic research on MGF's mechanisms in cellular biology.¹

Important Notice

MGF is intended exclusively for in vitro and in vivo (animal) laboratory research and is not approved for use in humans or animals. These findings do not establish safety, efficacy, or suitability for any human or animal application, and this product has not been evaluated by the FDA or any regulatory agency.

Product Information

MGF is supplied as a research reagent for laboratory use only, available in bulk quantity.

References

1. Zabłocka B, et al. Mechano-Growth Factor in Muscle Repair. Front Endocrinol. 2012;3:131.
2. Mills P, Dominique JC, Lafreniere JF, Bouchentouf M, Tremblay JP. A synthetic mechano growth factor E peptide enhances myogenic precursor cell transplantation success. Am J Transplant. 2007;7(10):2247-2259.
3. Zhang B, et al. Exp Cell Res. 2014;322(1):208-216.
4. Zhang B, et al. Biotechnol Lett. 2016;38(10):1817-1825.
5. Quesada A, et al. Exp Neurol. 2009;220(2):255-266.