NAD+ 500mg
Buy NAD+ 500mg :
| Unit Size | 500mg/vial |
| Unit Quantity | 1 vial |
| Purity (Mass Spectrometry and UV) | 97.70% |
| Sequence | N/A |
| Molecular Formula | C21H27N7O14P2 |
| Appearance | Lyophilized White Powder |
| Source | Chemical Synthesis |
| Storage | Lyophilized NAD+ is stable at room Temperature for 90 days, however it is best to store in a freezer below - 8c for any extended period of time. |
| Terms | The products we offer are intended for laboratory research use only. Please familiarize yourself with our terms of service prior to ordering. |
NAD+ 500mg
View Research Overview & References
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in all living cells and is studied for its role in cellular energy production and metabolism. NAD+ participates in redox reactions, serving as an electron transporter in the mitochondrial electron transport chain (ETC), which generates ATP. Research has examined changes in NAD+ levels in relation to cellular aging models and associated markers of metabolic and cellular changes.1
This NAD+ 500mg product is intended exclusively for in vitro laboratory research and is not approved for human or veterinary use. Laboratory research into NAD+ includes its role in cellular energy production, DNA repair signaling, and cellular aging models.2
Cellular Energy Production Research
In vitro studies on NAD+ have examined its role in cellular energy metabolism, including glycolysis, the citric acid cycle, and oxidative phosphorylation — metabolic pathways that generate ATP in cells. Research has examined the relationship between NAD+ availability and mitochondrial function markers in cell models of cellular aging.3,4
DNA Repair Signaling Research
NAD+ is studied for its role in DNA repair signaling, functioning as a substrate for enzymes including PARPs (Poly ADP-ribose polymerases) and sirtuins. Research has examined the activation of these enzymes in response to DNA damage in cell models.5 Sirtuins, a class of NAD+-dependent enzymes, are studied for their role in chromatin regulation and gene expression, including research on markers of inflammation and oxidative stress in cell models.
Neuronal Cell Research
Research into NAD+ has also examined its relationship to neuronal cell health markers in laboratory models. Studies have examined NAD+'s role in supporting axonal integrity markers in neuronal cell models.
Product Information
This NAD+ 500mg product is supplied as a white, lyophilized powder specifically for in vitro laboratory research. It is not intended for use in humans or animals, and has not been evaluated for safety or efficacy in humans or animals.
References
1. Gomes AP, Price NL, Ling AJ, et al. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell. 2013 Dec;155(7):1624-38.
2. Yoshino J, Baur JA, Imai SI. NAD+ intermediates: the biology and therapeutic potential of NMN and NR. Cell Metab. 2018;27(3):513-28.
3. Verdin E. NAD+ in aging, metabolism, and neurodegeneration. Science. 2015 Dec 4;350(6265):1208-13.
4. Cantó C, Menzies KJ, Auwerx J. NAD+ metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus. Cell Metab. 2015;22(1):31-53.
5. Liu L, Su X, Quinn WJ 3rd, et al. Quantitative analysis of NAD synthesis-breakdown fluxes. Cell Metab. 2018 Jan 9;27(1):106-121.
Storage Case (10)$9.99
