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| Unit Size | 10 mg/vial |
| Unit Quantity | 1 vial |
| Purity (Mass Spectrometry and UV) | 99.94% |
| Sequence | Ac-Nle-Asp-His-Arg-Trp-d-Phe-Lys-NH2 |
| Molecular Formula | C50H69N15O9 |
| Appearance | Lyophilized White Powder |
| Source | Chemical Synthesis |
| Storage | Lyophilized Melanotan II is Stable at room Temperature for 90 days, however it is best to store in a freezer below - 8c for any extended period of time. |
| Terms | The products we offer are intended for laboratory research use only. Please familiarize yourself with our terms of service prior to ordering. |
MELANOTAN II 10mg (Bulk)
Melanotan II is a synthetic peptide designed to mimic melanocyte-stimulating hormone (MSH), studied in vitro and in vivo (animal) laboratory research. Melanotan II has been used in various animal studies to investigate physiological processes such as metabolism, nerve-related signaling, and behavior. Melanotan II is intended strictly for research purposes and is not approved for human use.
In a study involving female rats, Melanotan II administration was associated with increased proceptive sexual behavior markers.1 Another study examining male rats found that Melanotan II administration was associated with changes in sexual behavior markers previously suppressed by induced psychological stress in the animal model.2
Research has also examined Melanotan II's effects on nerve-related signaling in animal models. In a sciatic nerve crush model, Melanotan II administration was associated with changes in sensory function recovery markers.3 Additionally, in a toxic neuropathy model induced by cisplatin, researchers observed differences in nerve damage markers following Melanotan II administration, compared to untreated animals in the model.3
Melanotan II's effects on metabolism have been examined in several animal studies. In one experiment, rats receiving daily Melanotan II injections showed reduced food and water intake and decreased weight gain markers. These effects were associated with changes in lipid mobilization markers in adipose tissue, rather than cell death markers.4 Additionally, Melanotan II was examined for its effects on glucose disposal markers in mice through central administration, independent of appetite-related measures in the animal model.5
Melanotan II is exclusively available for in vitro and in vivo (animal) laboratory research purposes and should only be used in controlled experimental settings. It is not approved for human or veterinary use, and all handling must comply with appropriate laboratory protocols. These findings do not establish safety, efficacy, or suitability for any human or animal application.
Melanotan II is supplied as a research reagent for laboratory use only, available in bulk quantity.
1. Rössler AS. The melanocortin agonist, melanotan II, enhances proceptive sexual behaviors in the female rat. Pharmacol Biochem Behav. 2006;85(3):514-521.
2. Miwa Y, Oyama N, Akino H, Yokoyama O. Effect of melanotan II, a melanocortin agonist, on sexual behavior suppressed by psychological stress in male rats [Abstract]. J Urology. 2012;187:e411.
3. Ter Laak MP, Brakkee JH, Adan RA, Hamers FP, Gispen WH. Melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol. 2003;462(1-3):179-183.
4. Choi YH, et al. MTII administered peripherally reduces fat without invoking apoptosis in rats. Physiol Behav. 2003;79(2):331-337.
5. Heijboer AC, et al. Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice. Diabetologia. 2005;48(8):1621-1626.