Buy Bulk MELANOTAN II 10mg (No Promo Codes)

MELANOTAN II 10 mg is a synthetic peptide hormone that is designed to mimic the effects of the natural hormone melanocyte-stimulating hormone (MSH) in the body. Various physiological processes have been explored through animal studies investigating the effects of melanotan II. 

In one study involving female rats, melanotan II was found to promote proceptive sexual behavior.1 Another study examined the effects of melanotan II on male rats' sexual behavior, revealing that the administration of melanotan II was able to restore suppressed sexual behavior caused by psychological stress.2 These findings suggest the potential use of melanotan II in treating psychological sexual disorders. 

Researchers reported the neuroregenerative and neuroprotective effects of melanotan II in rats. They used the sciatic nerve crush model as a means to investigate the neurotrophic properties of melanotan II. The findings revealed significant improvements in sensory function recovery following a crush injury to the sciatic nerve when melanotan II was administered. This suggests that MT-II possesses neuroregenerative properties.3 Moreover, when the rats were exposed to a toxic neuropathy induced by cisplatin, melanotan II was found to provide partial protection to the nerve. These results indicate that melanotan II can shield the nerve from damage caused by toxic insults.3 

Additionally, melanotan II was found to affect metabolism by mimicking the effects of leptin. In a separate study, rats were injected with melanotan II once a day for four days, resulting in decreased food and water intake as well as weight gain. The mechanism behind this effect was determined to be accelerated lipid mobilization in fat tissue, rather than apoptosis.4

Melanotan II's effects on metabolism were further investigated, revealing that central administration of the peptide increased glucose sensitivity in mice, leading to improved glucose disposal. Notably, this effect was found to be independent of melanotan II's well-known impact on food intake.5

While animal and in vitro studies can provide valuable insights into the potential effects of melanotan II, further research is necessary to fully understand the safety and efficacy of Melanotan II before it can be considered a safe and effective treatment.

References: 1. Rössler AS. The melanocortin agonist, melanotan II, enhances proceptive sexual behaviors in the female rat. Pharmacol Biochem Behav. 2006 Nov;85(3):514-21. 2. Miwa Y, Oyama N, Akino H, Yokoyama O. Effect of melanotan II, a melanocortin agonist, on sexual behavior suppressed by psychological stress in male rats. J Urology. 2012; 187;e411. 3. Ter Laak MP, Brakkee JH, Adan RA, Hamers FP, Gispen WH. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol. 2003 Feb 21;462(1-3):179-83. 4. Choi YH et al. MTII administered peripherally reduces fat without invoking apoptosis in rats. Physiol Behav. 2003 Jul;79(2):331-7. 5. Heijboer AC et al. Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice. Diabetologia. 2005 Aug;48(8):1621-6.