GHRP-2 Peptide 5mg

Growth Hormone Releasing Peptide-2 (GHRP-2) is a synthetic analog of ghrelin, a peptide that binds to the growth hormone secretagogue receptor (GHS-R). Research has characterized ghrelin's role in growth hormone (GH) release and receptor signaling.¹ GHRP-2 is studied for its similar interaction with GHS-R. This product is intended strictly for in vitro and in vivo (animal) laboratory research only and consists of six amino acids, with a molecular weight of 818 Da.

Receptor Mechanism Research

Laboratory research has examined GHRP-2's interaction with GHS-R and its effects on somatostatin signaling pathways, which are studied for their role in regulating GH release.⁵

Animal Model Research

In an ApoE-deficient mouse model, research examined GHRP-2's effects on vascular oxidative stress markers.³ Separately, animal research in a livestock model examined GHRP-2's effects on growth performance markers and muscle protein signaling.⁷ Laboratory research has also examined GHRP-2's effects on inflammatory markers, including tissue necrotic factor-alpha (TNF-α), in an animal model of liver tissue injury.

Receptor Pharmacology Research

Research has examined growth hormone-releasing peptides, including GHRP-2, in relation to cardiovascular system receptor signaling in laboratory models.¹⁰

Important Notice

GHRP-2 is provided strictly for in vitro and in vivo (animal) laboratory research only and is not approved for human or veterinary use. Any application outside of controlled research environments is strictly prohibited, and these findings do not establish safety, efficacy, or suitability for any human or animal application.

Product Information

GHRP-2 is supplied as a lyophilized powder (5 mg per vial) exclusively for in vitro and in vivo (animal) research use. The vial can be reconstituted with sterile water for laboratory applications.

References

1. Sun Y, Wang P, Zheng H, Smith RG. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4679-84.
2. Titterington JS, Sukhanov S, Higashi Y, Vaughn C, Bowers C, Delafontaine P. Growth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis. Endocrinology. 2009 Dec;150(12):5478-87.
3. Cheng J, Wu TJ, Butler B, Cheng K. Growth hormone releasing peptides: a comparison of the growth hormone releasing activities of GHRP-2 and GHRP-6 in rat primary pituitary cells. Life Sci. 1997;60(16):1385-92.
4. Hu R, Wang Z, Peng Q, Zou H, Wang H, Yu X, Jing X, Wang Y, Cao B, Bao S, Zhang W, Zhao S, Ji H, Kong X, Niu Q. Effects of GHRP-2 and Cysteamine Administration on Growth Performance, Somatotropic Axis Hormone and Muscle Protein Deposition in Yaks (Bos grunniens) with Growth Retardation. PLoS One. 2016 Feb 19;11(2):e0149461.
5. Muccioli G, Broglio F, Valetto MR, Ghè C, Catapano F, Graziani A, Papotti M, Bisi G, Deghenghi R, Ghigo E. Growth hormone-releasing peptides and the cardiovascular system. Ann Endocrinol (Paris). 2000 Feb;61(1):27-31.