September 2014

  1. What is AICAR Ribonuccleotide?

    In scientific terms, AICAR Ribonuccleotide, or AICAR, is an analog of AMP. Studies have indicated it is able to stimulate AMP-dependent proteins kinase activity in animal test subjects. Because of this, it is being researched on animal test subjects in scientific studies to determine whether it can help treat and protect against cardiac ischemic injury. This is a condition that can lead to myocardial infarction. What causes this health problem is a lack of oxygen and flow of blood to the myocardium. It wasn’t until the 1980s, when the peptide was first researched on animal test subjects as a way to assist the heart with getting blood while having surgery. Research also shows that it could potentially treat other illnesses like diabetes, since it can boost the metabolic activity of tissues by changing the muscles’ physical composition in animal test subject studies. Medical Use of AICAR Ribonuccleotide AICAR Ribonuccleotide has shown it regulates various intracellular systems in animal test subjects, such as cellular glucose uptake, biogenesis of mitochondria, glucose transport 4 and B-Oxidation of fatty acids. When researched with animal test subjects, it has also shown to promote the storage of nutrients on a cellular level. In return, this enhances energy production. AICAR has been used in animal test trials, which had results that indicate the research peptide's ability to regulate the functions of the heart. Scientifically put, the peptide is able to go into cardiac cells to inhibit enzyme production (i.e. adenosine kinase and adenosine deaminase). With the ability to block the enzymes, an increase in glucose (on a cellular level) and p38 mitogen-activated protein kinases A and B occurs in the skeletal muscle’s tissues. It also stops programmed cellular death (or apoptosis) from taking place. When this peptide was studied on test subjects, the increase in the production of glucose and oxygen allowed the subject’s metabolism to reach a homeostasis level more efficiently. Potential Benefits of AICAR Due to the amount of testing that has been done, scientists have come up with theoretical benefits that can be linked to peptide. As mentioned above, one of the benefits happens to be AICAR’s ability to assist with cardiac ischemic injuries. Ischemic conditions can exist in many different areas of the animals test subject's body and in different forms, such as an embolism or thrombosis. In the case of cardiac ischemic injuries, it is directly related to the myocardium. Some cardiac ischemic episodes are asymptomatic, but can be linked to insufficient blood flow to the brain. This is called angina pectoris. Research studies have shown that heart attacks too are caused by restriction of blood flow to the heart. Studies have also shown that AICAR Ribonuccleotide can help to treat animal test subjects heart muscle after a heart attack has occurred due to ischemic injury. Side Effects Associated with AICAR Through the tests that were performed on animal test subjects using AICAR, it has been proven that there are a couple of side effects associated with it. Since peptides deal mainly with the heart, it’s not surprising that the side effects lie here as well. Some of the side effects on animal test subjects include heart valve development defects and abnormal heart tissue growth. Disclaimer: AICAR Ribonuccleotide should not be used or consumed by humans. The research conducted with this peptide was for experimentation and research purposes only. It should not be purchased for any other use. If purchased, AICAR should only be used under experimental circumstances that are under strict laboratory guidelines. Safety equipment should be worn and used when conducting experiments with AICAR. In the event that exposure occurs, immediate cleansing should take place to avoid harm to the individual. It’s likely that studies for AIRCAR will continue over the next couple of decades. Doing so may one day bring about more ideas for treating and preventing ischemic injuries in animal test subjects.
  2. How Does Letrozole Work?

    Letrozole is the generic name of a currently tested research liquid called Femara. Scientific studies have been conducted on animal test subjects to determine whether this research liquid can be used to treat ovulation issues and unexplained infertility in different test subjects. Letrozole is a research liquid that is classified as an aromatase inhibitor. This research liquid has also been used in animal test subject studies for the treatment of cancer in breast tissue. How Letrozole is used for Fertility When animal test subjects are exposed to this research liquid, it has shown to inhibit the enzyme aromatase, which then causes estrogen levels to be suppressed. Studies on animal test subjects have shown to causes the brain and pituitary gland to release larger amounts of follicle stimulating hormones, or FSH. Animal test subjects that had polycystic ovary syndrome or anovulation (issues with ovulating), the FSH increase causes a mature follicle to develop within the ovary and cause egg ovulation. In the medical world, this is known as “induction of ovulation”. Letrozole is also being studied on animal test subjects that are already able to ovulate, but are still having problems getting pregnant. When researched, Letrozole has shown to causes the development of multiple follicles, which results in multiple eggs being released. Scientific studies on animal test subjects indicate this may help to increase chances of animal test subjects from becoming pregnant during a natural menstrual cycle. The scientific term for the process of multiple eggs and follicles being produced is controlled ovarian hyper stimulation or superovulation. Clomid Vs. Letrozole Clomid, also known as clomiphene citrate, is another research liquid that is being studied with animal test subjects to help stimulate ovulation when it can’t be done naturally on their own. Some of the animal test subject concluded that Clomid didn’t work for researched Letrozole and received favorable results. The following results were determined:
    • Some of the test results who didn’t respond to Clomid had their ovulation induced when Letrozole was used.
    • Some of the animal test subjects that used Clomid and never got pregnant used Famara and conceived.
    • Unpleasant side effects results in some of the test subjects that used Clomid, making Famara more favorable for them.
    Success Rate of Famara-Letrozole The chances of test subjects becoming pregnant with Famara are pretty much the same as if they used Clomid. This all comes down to the age of the test subject, sperm quality and status of the fallopian tubes. A higher success rate was found in test subjects that weren’t able to ovulate on their own. The following conditions improve the success rate of test subjects by 15% per month:
    • No other problems with fertility are found in the animal test subjects
    • The test subject is younger than half of their natural life cycle.
    The lowest success rate was in animal test subjects that had unexplained infertility problems, but still ovulate on their own. Other Uses for Letrozole This research liquid has also been used on postmenopausal animal test subjects who have had surgery for hormone receptor-positive early breast cancer and advanced breast cancer. It has also been tested on subjects that have received five years of tamoxifen therapy. Research has been done on animal test subjects that are in menopause (natural or artificially induced) who have cancer that’s spread from their breast to other areas of the body, and have already had anti-estrogen therapy. Letrozole is being tested in breast cancer animal test subjects because it inactivates an enzyme called aromatase, which prevents estrogen production. Estrogen is a known source for cancer cell growth. Disclaimer: Letrozole is a research liquid that has been used for scientific research on animal test subjects for breast cancer and infertility. It is advised that you only purchase this product with the intention of vitro laboratory research and experimentation only. It is not intended for human use or consumption.
  3. What is Selank Peptide

    The heptapeptide Selank is one of the newer peptides undergoing extensive research of late. Researchers are trying to understand what the peptide does, how it interacts with different systems within the body of the different test subjects, and what the effects of this peptide are under different experimental circumstances. So far, researchers are learning quite a bit about how this peptide is nearly a synthetic reproduction of tuftsin, which most bodies create naturally within the spleen.

    The Origins of Selank

    Selank was originally developed out of the Institute of Molecular Genetics, at the Academy of Sciences in Russia. The current peptide sequence has been found to be Thr-Lys-Pro-Arg-Pro-Gly-Pro. This is showing researchers that it can inhibit the enzymes that are involved in the degradation of endogenous peptides as well as enkephalins. That is where the basis of the research began with selank. The initial results were very promising when researchers began looking at the anxiolytic and nootropic effects of the peptide on the test subjects. This peptide began modulating Interleukin-6 expressions, and the brain-derived neurotropic factors in the test subjects of choice, in this case, rats.

    What Researchers Are Discovering About Selank

    So far, the most important discovery that researchers have made about selank is that it is showing great promise in reducing anxiety within the test subjects it has been tested on. There are no sedation effects being exhibited by the test subjects, but the anxiety and fear the animals were showing prior to exposure to selank is greatly reduced, or even gone in some cases. To make matters even better, this peptide has not shown any type of withdrawal symptoms after exposure to the peptide has stopped, and there are no signs of addictive tendencies being shown by any of the test subjects after repeated exposure to the peptide. Another benefit that researchers have found is that the risk toxicity associated with exposure to selank is incredibly low. In fact, in numerous experiments, researchers exposed test subjects to much higher than normal doses, up to 500 times the standard dose, and found no ill effects. This makes the risk of any type of overdose with this peptide nearly negligible, allowing for researchers to be able to continuously perform experiments without having to worry about giving any of the test subjects a dose that is slightly too high, harming the animal. This is helping researchers understand the importance in the regulation of both enkephalins and the endogenous peptides within the body when it comes to controlling anxiety. The more test subjects are exposed to this peptide, the more researchers are learning about the right levels each body needs to have in order to control anxiety. Through this discovery, researchers have also found that the more each test subject is exposed to selank, the stronger their immune system becomes, and the better their body is able to fight off illnesses. DISCLAIMER: This peptide was solely created for research and experimental purposes, and should not be used for any purpose outside of experiments and research. Ingestion of selank is dangerous, and should not be attempted under any circumstances. Researchers using this peptide should wear all types of protective gear when using it for experiments, and should incidental contact occur, all attire should be thoroughly cleaned immediately. Selank has the capability of teaching researchers a lot when it comes to how to boost an immune system and how to avoid anxiety. The more researchers can learn through test subject experimentation with selank, the more they will be able to learn about how the body works, and the better they will be able to set up future experiments to continue learning even more.
  4. What is Sermorelin Used For

    Sermorelin is one of the most commonly used peptides in growth research around. It is the smallest chain of workable amino acids with 29 acids in a row, which allows research to take place on how growth occurs in different types of exposure. The potential educational experiences that could come from sermorelin are quite lengthy due to the fact that this peptide can be synthesized so easily. The potential uses of this peptide are only now being discovered as research is just starting to put together what type of experiments this peptide works well with.

    What Does Sermorelin Do?

    Sermorelin currently has shown the ability to increase the test subject's natural levels of secretion of the pituitary gland's hormones for growth. This had given some test subjects the ability to start growing again after natural growth had stopped. This increase accompanied different doses, with the most effective being the dose that was given daily. The effect hit the test subjects very quickly, as it has a very short half-life of only 12 minutes on average. So far it has shown growth in the cells that were exposed to the sermorelin within an experimental setting, as well as growth in the test subjects that were exposed to the peptide. There has been no evidence of any type of toxicity within the test subjects genes after exposure to sermorelin, but this has not been thoroughly tested. This peptide has also not been tested on pregnant or lactating test subjects, so the harm this may or may not cause is still unknown.

    What Is Sermorelin Used For?

    Currently, the most common use for sermorelin is that of research. Many companies are trying to understand what processes within the body turn on or turn off growth, and this peptide allows for this particular view to be studied. Since the synthesized peptide is so similar to the naturally occurring growth hormones, it allows researchers to get a very solid perspective on how different types of growth occur and how to stop that growth once it's started. The research environment allows for the researchers to view the growth on a cellular level under microscopes, which can help open up roads to new types of research in the future. If a researcher is looking to do long-term research, the short life of Sermorelin is not going to work very well. However, for a researcher looking to do quick experiments that are easy to repeat to verify information and results, sermorelin is the ideal peptide for this purpose. It has the ability to initiate growth quickly, turn off quickly, and start the experiment over again in a matter of minutes, allowing researchers to view what repeated exposure may do to the test subjects. DISCLAIMER: Sermorelin is created and distributed for research purposes only. It can be harmful if ingested by human beings, and should be avoided at all times. Should you desire to perform research with Sermorelin, all safety precautions should be taken prior to starting the experiment. Do not consume this peptide under any circumstances, and if accidental ingestion occurs, medical help should be sought out immediately. Sermorelin has the potential to teach researchers quite a bit under the right circumstances. If the goal is to learn about growth on a fast, cellular level, Sermorelin should be the peptide of choice. The quick reaction of cells with the peptide makes the results found easy to replicate for verification purposes, and allows researchers to quickly and easily make their results known to the public. This short string of amino acids is quite similar to those found naturally within the body of test subjects, making it ideal for study and experimentation purposes.
  5. What is Cabergoline

    In the world of research liquids, Cabergoline is among one that is teaching scientists quite a bit. They have been studying the effects on numerous test subjects, but the ones that are showing the most promise in terms of research are rats. Researchers are able to see the results quickly, and change their experiments minimally to learn more about what the liquid itself is doing to the test subject's body. The benefits that Cabergoline could offer in terms of knowledge are growing with each new experiment that is being performed.

    What Does Cabergoline Interact With?

    First discovered in 1981, and patented in 1985, Cabergoline is a synthetic liquid that originated with researchers in Italy. This ergot derivative has shown impressive results in inhibiting prolactin cells on D2 receptors for dopamine. Researchers are regularly using this as a first line of defense when managing prolactins, because this research liquid seems to stick to more D2 receptors than other research liquids in the same family. However, it also sticks with other receptors, such as D3 and D4 receptors, and some of the 5-HT receptors.

    What Are the Specifications of Cabergoline?

    So far, researchers have discovered that Cabergoline has a half-life that is between 63 and 69 hours, allowing for researchers to perform long-term experiments and see how different test subjects and their cells react to Cabergoline exposure. Once the liquid starts to break down in preparation to exit the body, researchers have found the majority of the remnants to be excreted in the feces of the test subject, instead of the urine. There is very little information on whether or not this research liquid is safe during pregnancy, so those experiments are yet to come. However, rats have shown that it is crossing over into their milk, so it is not recommended to be experimented on during lactation. When it was used during lactation, it did show that the research liquid suppressed the milk production in the female rats, and has since been used to help treat false pregnancies in dogs so help dry up the milk supply.

    What Side Effects Have Been Common with Cabergoline?

    Researchers have found that most of the side effects that come along with exposure to Cabergoline are totally dependent on the dosage the test subject is exposed to. The more research liquid the rat was exposed to, the higher its chances of having one of these side effects. The most common side effects were nausea, dry mouth, low blood pressure, and constipation. Some of the less common side effects included disturbances in the test subject's sleeping cycles (either trouble sleeping or trouble staying awake), vertigo, irregular heartbeats, depression, and edema. Researchers also noticed that some of the test subjects also had increases in their levels of liver enzymes, but showed no adverse side effects of these increases. Cabergoline is a very valuable liquid in terms of what it can teach researchers. They are able to see the differences that each dose can make on different cells over longer times than many other research liquids. The side effects that researchers are seeing with exposure to Cabergoline are minimal in comparison to the side effects that come with many of the ailments this research liquid is teaching them about; allowing them to see what damage is being done to the body by the ailments directly. This is helping researchers learn more about the body's response to these ailments, and could help uncover a way to treat them in the future for these test subjects. DISCLAIMER: Cabergoline is not intended for human use or human consumption in any form. Exposure to this research liquid could cause harm, and should be avoided at all costs. These research liquids are for research purposes only, and should not be used for any other circumstance.

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